منابع مشابه
Dietary Protein, Metabolism, and Aging.
Dietary restriction (DR), a moderate reduction in food intake, improves health during aging and extends life span across multiple species. Specific nutrients, rather than overall calories, mediate the effects of DR, with protein and specific amino acids (AAs) playing a key role. Modulations of single dietary AAs affect traits including growth, reproduction, physiology, health, and longevity in ...
متن کاملDietary Protein Considerations to Support Active Aging
Given our rapidly aging world-wide population, the loss of skeletal muscle mass with healthy aging (sarcopenia) represents an important societal and public health concern. Maintaining or adopting an active lifestyle alleviates age-related muscle loss to a certain extent. Over time, even small losses of muscle tissue can hinder the ability to maintain an active lifestyle and, as such, contribute...
متن کاملRegulation of Protein Metabolism in Exercise and Recovery Aging, exercise, and muscle protein metabolism
Koopman R, van Loon LJ. Aging, exercise, and muscle protein metabolism. J Appl Physiol 106: 2040–2048, 2009. First published January 8, 2009; doi:10.1152/japplphysiol.91551.2008.—Aging is accompanied by a progressive loss of skeletal muscle mass and strength, leading to the loss of functional capacity and an increased risk of developing chronic metabolic disease. The age-related loss of skeleta...
متن کاملInvolvement of Drosophila uncoupling protein 5 in metabolism and aging.
A novel uncoupling protein, UCP5, has recently been characterized as a functional mitochondrial uncoupler in Drosophila. Here we demonstrate that UCP5 knockout (UCP5KO) flies are highly sensitive to starvation stress, a phenotype that can be reversed by ectopic neuronal expression of UCP5. UCP5KO flies live longer than controls on low-calorie diets, have a decreased level of fertility, and gain...
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ژورنال
عنوان ژورنال: Annual Review of Biochemistry
سال: 2016
ISSN: 0066-4154,1545-4509
DOI: 10.1146/annurev-biochem-060815-014422